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DOSING FOR elective surgery

DOSING FOR elective surgery

Reduction of allogeneic red blood cell (RBC) transfusions in patients undergoing elective, noncardiac, nonvascular surgery1

PROCRIT® is indicated to reduce the need for allogeneic RBC transfusions among patients with perioperative hemoglobin >10 g/dL to ≤13 g/dL who are at high risk for perioperative blood loss from elective, noncardiac, nonvascular surgery. PROCRIT® is not indicated for patients who are willing to donate autologous blood pre-operatively.

PROCRIT® has not been shown to improve quality of life, fatigue, or patient well-being.

PROCRIT® is not indicated for use:

Patient scheduled for elective, noncardiac, nonvascular surgery

Patient scheduled for elective, noncardiac, nonvascular surgery

*Other causes of anemia may include vitamin deficiency, metabolic or chronic inflammatory conditions, bleeding, etc.

Hb=hemoglobin; U=units.

PROCRIT® has 2 dosing options1

Dosing Options Calendar

Weekly

  • Established dosing for elective, noncardiac, nonvascular surgery patients
  • PROCRIT® 600 U/kg SC in 4 doses administered 21, 14, and 7 days before surgery and on the day of surgery
Dosing Options Calendar

Daily

  • Established dosing for elective, noncardiac, nonvascular surgery patients
  • PROCRIT® 300 U/kg per day SC for 15 days total: administered daily for 10 days before surgery, on the day of surgery, and for 4 days after surgery

Deep venous thrombosis prophylaxis is recommended during PROCRIT® therapy. Please see WARNINGS AND PRECAUTIONS, section 5.1, of the FULL PRESCRIBING INFORMATION to learn more.

PROCRIT® is contraindicated in patients with uncontrolled hypertension, pure red cell aplasia (PRCA) that begins after treatment with PROCRIT® or other erythropoietin protein drugs, or serious allergic reactions to PROCRIT®. PROCRIT® from multiple-dose vials contains benzyl alcohol and is contraindicated in neonates, infants, pregnant women, and lactating women.1 Please see the FULL PRESCRIBING INFORMATION to learn more.

References

  1. PROCRIT® (epoetin alfa) Prescribing Information. Janssen Products, LP.
  2. Patel MS, Carson JL. Anemia in the preoperative patient. Med Clin North Am. 2009;93(5):1095-1104.
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